Substrate: WEE 1 tyrosine kinase (Dual specificity kinase)
Seq-ID: P30291 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-50988   1433B_HUMAN
MINT-3295375   1433Z_HUMAN
MINT-3975741   1433S_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
magnesium ion binding,
protein serine/threonine kinase activity,
non-membrane spanning protein tyrosine kinase activity,
ATP binding,
protein binding		 nucleoplasm protein amino acid phosphorylation,
cell division,
mitosis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 53 EGSGHSTGEDSAFQEPDSPLP PLK1 15070733
LTP
0.36
 MOD_PLK
 PLK1 PBD -
0.96
 - medium
S 53 EGSGHSTGEDSAFQEPDSPLP PLK1 16085715
LTP
0.36
 MOD_PLK
 PLK1 PBD -
0.96
 - medium
S 121 GDSWEEEGFGSSSPVKSPAAP - 16085715
LTP
0.29
 - -
0.76
 - medium
S 123 SWEEEGFGSSSPVKSPAAPYF CDK1 15070733
LTP
0.54
 MOD_CDK_SPxK_1
 - -
0.73
 - medium
S 123 SWEEEGFGSSSPVKSPAAPYF CDK1 16085715
LTP
0.54
 MOD_CDK_SPxK_1
 - -
0.73
 - medium
S 127 EGFGSSSPVKSPAAPYFLGSS - 17081983
HTP
0.21
 - -
0.66
 - medium
S 139 AAPYFLGSSFSPVRCGGPGDA - 15302935
HTP
0.92
 - -
0.65
 - medium
S 139 AAPYFLGSSFSPVRCGGPGDA - 17081983
HTP
0.92
 - -
0.65
 - medium
S 139 AAPYFLGSSFSPVRCGGPGDA - 17192257
HTP
0.92
 - -
0.65
 - medium
S 139 AAPYFLGSSFSPVRCGGPGDA - 18220336
HTP
0.92
 - -
0.65
 - medium
S 165 GARRAGEGRRSPRPDHPGTPP - 17081983
HTP
0.97
 - -
0.94
 - medium
T 173 RRSPRPDHPGTPPHKTFRKLR - 17192257
HTP
1.00
 - -
0.84
 - medium
S 642 LIGKKMNRSVSLTIY       - 15150265
LTP
0.98
 SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3		 -
0.28
 - medium
S 642 LIGKKMNRSVSLTIY       - 15964826
LTP
0.98
 SFN 14-3-3;
YWHAB 14-3-3;
YWHAE 14-3-3;
YWHAG 14-3-3;
YWHAH 14-3-3;
YWHAQ 14-3-3;
YWHAZ 14-3-3		 -
0.28
 - medium

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